El objetivo del presente trabajo es caracterizar el material particulado PM 2.5 y PM 10 presente en el aire de Medellín y evaluar su capacidad de promover la respuesta inflamatoria y las infecciones virales respiratorias. Se cuantificará el efecto de este material sobre la expresión de los componentes de los inflamasomas, de las citoquinas proinflamatorias, del efecto citotóxico y en la replicación viral en cultivos celulares, así como los cambios histo-patológicos pulmonares desarrollados en un modelo murino de exposición aguda al PM del aire de Medellín.
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Dataset SARS + PM
Dataset SARS + PM
May 16, 2023
Hernández, Juan Carlos; Gómez, Diana Maryory; Zapata Builes, Wildeman; Aristizabal Tique, Victor Hugo; Taborda. Natalia Andrea; Porras López, Jazmín; Narvaez, Jhon Fredy; Rugeles López, María Teresa; Marin Palma, Leidy Damariz, 2023, "Dataset SARS + PM", https://doi.org/10.57924/JAP0D4, Papyrus, V1, UNF:6:4DG0XLzX+vo3QpIeZbC6FA== [fileUNF]
Experimental ELISA and qPCR data, from inflammatory markers in human primary cells, in vitro-exposed to particulated matter.
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